Peer-reviewed publications

Papers, errata and supplements from the MSC-NTF program in the peer-reviewed literature.

22 items

All publications and presentations

April 2024
Peer-reviewed
Debamestrocel multimodal effects on biomarker pathways in amyotrophic lateral sclerosis are linked to clinical outcomesMuscle & NerveView source
September 2022
Peer-reviewed
Evaluation of neurotrophic factor secreting mesenchymal stem cells in progressive multiple sclerosisMultiple Sclerosis JournalView source
August 2022
Peer-reviewed
Erratum to: A randomized placebo-controlled Phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosisMuscle & NerveView source
December 2021
Peer-reviewed
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosisMuscle & NerveView source
January 2021
Peer-reviewed
MSC-NTF (NurOwn®) exosomes: a novel therapeutic modality in the mouse LPS-induced ARDS modelStem Cell Research & TherapyView source
August 2020
Peer-reviewed
Effects of MSC-NTF cells on T and B regulatory cell function in ALSAmyotrophic Lateral Sclerosis and Frontotemporal DegenerationView source
November 2019
Peer-reviewed
NurOwn, phase 2, randomized, clinical trial in patients with ALSNeurologyView source
November 2017
Peer-reviewed
miRNA profiling of NurOwn: mesenchymal stem cells secreting neurotrophic factorsStem Cell Research & TherapyView source
2017
Peer-reviewed
Long term beneficial effect of neurotrophic factors-secreting mesenchymal stem cells transplantation in the BTBR mouse model of autismBehavioural Brain ResearchView source
2017
Peer-reviewed
Concise review: mesenchymal stem cells in neurodegenerative diseasesStem CellsView source
January 2016
Peer-reviewed
Safety and clinical effects of mesenchymal stem cells secreting neurotrophic factor transplantation in patients with amyotrophic lateral sclerosisJAMA NeurologyView source
2014
Peer-reviewed
Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cellsClin Transl MedView source
2014
Peer-reviewed
Rare combination of myasthenia and motor neuronopathy, responsive to MSC-NTFstem cell therapyMuscle NerveView source
2012
Peer-reviewed
Intrastriatal transplantation of neurotrophic factor-secreting human mesenchymal stem cells improves motor function and extends survival in R6/2 transgenic mouse model for Huntington’s diseasePLoS CurrView source
2012
Peer-reviewed
Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity: a potential therapy for Huntington’s diseaseExp NeurolView source
2012
Peer-reviewed
Differentiated mesenchymal stem cells for sciatic nerve injuryExp NeurolView source
2010
Peer-reviewed
Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transectionInvest Ophthalmol Vis SciView source
2009
Peer-reviewed
Intracerebroventricular transplantation of human mesenchymal stem cells induced to secrete neurotrophic factors attenuates clinical symptoms in a mouse model of multiple sclerosisJ Mol NeurosciView source
2009
Peer-reviewed
Protective effects of neurotrophic factor-secreting cells in a 6-OHDA rat model of Parkinson diseaseStem Cells and DevelopmentView source
2009
Peer-reviewed
Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseasesIsr Med Assoc JView source
2009
Peer-reviewed
Induction of adult human bone marrow mesenchymal stromal cells into functional astrocyte-like cells: potential for restorative treatment in Parkinson’s diseaseJ Mol NeurosciView source
2008
Peer-reviewed
Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imagingStem CellsView source

BrainStorm's autologous MSC-NTF cell therapy (NurOwn^®, debamestrocel) is investigational and has not been approved by the FDA or any other regulatory authority.